It has cholinomimetic effect anavar side effects through reversible inhibition of cholinesterase and enhance the action of acetylcholine. It improves neuromuscular transmission, increases the motility of the gastrointestinal tract, increases the tone of the bladder, bronchial secretion of exocrine glands, causes bradycardia, weak miosis, spasm of accommodation. It has no central action.
With caution: arterial hypotension anavar side effects, decompensated heart failure, renal failure, acute myocardial infarction, peptic ulcer of the stomach, bradycardia, diabetes, Parkinson’s disease, gallstone disease in the absence of obstruction, urolithiasis in the absence of obstruction, a condition after operations on the gastrointestinal tract, liver insufficiency, hyperthyroidism.
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Use during pregnancy and during breastfeeding
Pyridostigmine does not have teratogenic effects, but has fetotoxic. The drug can cause premature birth, especially when used in the last weeks of pregnancy.
Pyridostigmine passes into anavar side effects breast milk. In appointing the drug breast-feeding should be discontinued.
Dosing and Administration
Inside, squeezed water.
When the initial symptoms of the disease the recommended dose – 1 / 2-1 tablet (30-60 mg) 1-2 times a day.
With the progression of the disease – 1-3 tablets (60-180 mg) 2-4 times day. The maximum daily dose -. 12 tablets (720 mg)
Dosing pyridostigmine in myasthenia gravis conducted strictly individually depending on the severity anavar side effects of the disease and the patient’s response to treatment. Therefore, dosage regimens are recommended for this indication should be considered as indicative. Treatment of patients with kidney disease. Patients with kidney disease the drug is administered in lower doses, t. To. Pyridostigmine in unchanged form excreted mainly by the kidneys. Therefore, the necessary dose is selected individually for each patient, depending on the drug.
Allergic reactions, increased sweating, increased salivation and lacrimation, increased secretion of bronchial glands, nausea, vomiting, diarrhea, cramping abdominal pain, caused by increased intestinal peristalsis, frequent urge to urinate, muscle tremors, skeletal muscle spasms, muscle weakness and accommodation anavar side effects disorders. In applying the drug in higher doses may develop bradycardia and decreased blood pressure. In very rare cases, there are rashes on the skin.
Symptoms: increased secretion of the lacrimal, salivary and sweat glands, skin redness, severe weakness, blurred vision, cramps, dizziness, nausea, vomiting, involuntary defecation and urination, intestinal colic, bronchospasm, pulmonary edema, severe or progressive muscle weakness, paralysis of the respiratory muscles , lowering blood pressure, collapse, bradycardia, paradoxical tachycardia or cardiac arrest. Treatment: the specific antidote is atropine, which is administered intravenously (slowly) at a dose of 1-2 mg. Depending on the frequency of the pulse starting dose is administered if necessary after 2-4 hours again. You should also use activated carbon, other chelators and gastric lavage. Necessary to control fluid and electrolyte balance of the body, breathing and cardiac monitoring. When respiratory failure or cardiac arrest is necessary to conduct appropriate resuscitation.
Interaction with other drugs
Atropine weakens the m-cholinomimetic effect of pyridostigmine bromide (bradycardia and hypersecretion), but its effect on the skeletal muscles. Pyridostigmine increases the effects of depolarizing muscle relaxants, morphine and its derivatives, barbiturates. Incompatible with ethanol. M-holinoblokatory, ganglioplegic, quinidine, procainamide, local anesthetics, tricyclic antidepressants, antiepileptic and antiparkinsonian drugs reduce the severity of the action of pyridostigmine bromide.
The treatment should be careful when driving vehicles and occupation of potentially hazardous activities that require high concentration and psychomotor speed reactions.
In the treatment of patients is strictly forbidden to drink alcohol.
If the patient has forgotten to take timely the next dose, do not take a double dose to the next administration.
Tablets 60 mg.
100 tablets in a bottle of brown glass with a plastic cover with a control of the first opening.
1 bottle with instructions for use in a cardboard box.
After first opening – 6 months.
Do not use the drug after the expiry date stated on the package.
Store at temperatures not above 25 ° C. Keep out of the reach of children.
Conditions of supply of pharmacies
On prescription. how much to inject for weight loss
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