Drug containing the macro element anavar reviews potassium, Potassium makes up for the deficit. Potassium excitability and reduces conduction in the myocardium attenuates the toxic effect of cardiac glycosides, without affecting their positive inotropic effect.In small doses, K + dilates coronary vessels, in large – narrows. It participates anavar reviews in the process of nerve impulses. Enables many cytoplasmic enzymes regulates intracellular osmotic pressure, protein synthesis, amino acid transport. Improves the reduction of skeletal muscle in muscular dystrophy, myasthenia gravis.
Following oral administration is easy and anavar reviews virtually any number of passively absorbed (absorption – 70%), as the concentration (as a food, as released from the dosage form) above in the lumen of the small intestine than in the blood. From tablets retard gradually and slowly released throughout the digestive tract. The ileum and colon K + is released into the gut lumen by the principle of the conjugate exchange with Na + and excreted in bile (10%). Distribution of K + in the body lasts for about 8 hours after administration: The half-life in the absorption phase -1.31 hours; release time of retard tablets -6 hours.
Hypersensitivity to the drug, hyperkalemia, complete AV block, adrenal insufficiency, chronic renal insufficiency, concomitant therapy potassium-sparing diuretics, metabolic disorders (acidosis, hypovolemia with hyponatremia), erosive and ulcerative lesions of the gastrointestinal tract, pregnancy, lactation. Age up to 18 years.
Dosing and Administration
The dose is determined individually depending anavar reviews on the disease and the concentration of potassium in the blood plasma. Assign 1 – 2 g / day (based on potassium chloride), if necessary to increase the dose of 6 g / day.
On the part of the digestive tract: nausea, vomiting, diarrhea, flatulence, abdominal pain, gastrointestinal ulceration of the mucous membranes, gastrointestinal bleeding, perforation, and bowel obstruction.From the nervous system: paresthesia, muscle weakness, confusion. Cardio-vascular system: decrease in blood pressure, arrhythmias, heart block, cardiac arrest. Other: hyperkalemia, allergic anavar reviews reactions.
Symptoms: hyperkalemia (muscle hypotonia, paresthesia, slowing AV conduction, arrhythmias, heart failure). Early clinical signs of hyperkalemia usually appear at the K + concentration in the serum of more than 6 mEq / L: sharpening of the T wave, widening of the complex OK5. More severe symptoms of hyperkalemia – muscle paralysis and cardiac arrest – are developing at a concentration of the K + 9-10 mEq / L. Treatment: PO / a – ??sodium chloride; if necessary anavar reviews hemodialysis and peritoneal dialysis.
Interaction with other medicinal
Potassium-sparing diuretics, potassium supplements, ACE inhibitors, NSAIDs increase the risk of hyperkalemia. It reduces side effects of cardiac glycosides. Enhances the effect of quinidine, disopyramide side effects.
During treatment necessary to control the content of K + in the blood serum, the ECG, the treatment of hypokalemia – control of acid-base status (CBS). Safety and efficacy of potassium chloride in children have not been established. If necessary, use during pregnancy should be weighed against the expected benefit to the mother and the potential risk to the fetus. During the period of lactation should decide the issue of termination of breastfeeding. A diet with a high content of sodium chloride increases the excretion of K + excreted. Note that hyperkalemia leading to death, can develop rapidly and be asymptomatic.
The release form
: 10 tablets in blister. 3 blisters (30 tablets) is placed in a cardboard box with instructions for use.
In a dry and reach of children, at a temperature of 15 to 30 ° C.
3 years. Do not use after the date printed on the packaging.