Improves brain metabolism, increasing glucose and oxygen consumption of brain tissue. Increases resistance of neurons to hypoxia; enhancing glucose transport to the brain through the blood-brain barrier; It translates the process of disintegration of glucose to energy more economical, aerobic pathway; selectively blocks calcium-dependent phosphodiesterase; increases the levels anavar cycle for women of adenosine monophosphate and cyclic guanosine monophosphate exchange enhances brain noradrenaline and serotonin; stimulates the ascending branch of the noradrenergic system, has an antioxidant effect. Reduces the aggregation of platelets and increased blood viscosity; increases the deforming ability of red blood cells and red blood cells block the recycling of adenosine; enhances oxygen release by red blood cells. It enhances the neuroprotective action of anavar cycle for women adenosine. Increases cerebral blood flow; reduces the resistance of cerebral vessels without significant changes in the systemic circulation parameters (blood pressure, minute volume, heart rate, total peripheral resistance). Not only does not have “steal” effect, and increases blood flow, especially in ischemic brain regions with low perfusion. rapidly absorbed, at 1 h after oral administration to reach the maximum blood concentration. Absorption takes place mainly in the proximal gastrointestinal tract. When passing through the intestinal wall is not metabolized.
Acute phase of a hemorrhagic stroke, a severe form of coronary heart disease, severe arrhythmia and known hypersensitivity to vinpocetine and lactose intolerance. Pregnancy and lactation: Pregnancy, because vinpocetine crosses the placental barrier. Thus its concentration in the placenta and fetal blood is lower than in the blood of pregnant. At high doses may placental bleeding and spontaneous abortion, probably due to increased placental blood supply. Lactation: for an hour in the breast milk gets 0.25% of the dose of the drug. In applying the drug must stop breastfeeding. Children younger than 18 years (due to lack of data)
DOSAGE AND ADMINISTRATION
The course of treatment and dosage is determined by the attending physician.
Inside, after a meal.
Usually a daily dosage of 15-30 mg (5-10 mg 3 times a day).
The initial daily dose is 15 mg. The maximum daily dose of 30 mg. The therapeutic effect is about a week from the beginning of treatment. Course of treatment 1-3 months.
In the kidney and liver drug administered in the usual dose, absence of cumulation allows for long-term treatments.
Side effects during treatment with the drug is rarely detected. Since the cardiovascular system: ECG changes (depression ST, prolongation of QT interval); tachycardia, arrythmia, however, a causal anavar cycle for women relationship has not been proved since in natural populations of these symptoms occur with the same frequency; labile blood pressure, feeling the tides. On the part of the central nervous system: sleep disorders (insomnia, excessive sleepiness), dizziness, headache, fatigue (these symptoms may be manifestations of the underlying disease), increased sweating. On the part of the digestive system: dry mouth, nausea, heartburn. Allergic skin reactions.
At present, data on overdose vinpocetine limited.
Treatment of overdose: gastric lavage, activated charcoal, symptomatic therapy.
interaction was observed while the use of beta-blockers (hloranolol, pindolol) Klopamid, glibenclamide, digoxin, acenocoumarol and hydrochlorothiazide, imipramine
Concomitant use Cavinton ® and methyldopa sometimes caused some increase in the hypotensive effect, so if such treatment is required regular blood pressure control.
Despite the lack of evidence supporting the possibility of interaction, it is recommended to be cautious while appointing a central drugs, antiarrhythmic and anticoagulation action.
The presence of prolonged QT interval syndrome and receiving drugs that cause lengthening of the QT interval, requires periodic ECG monitoring.
Tablets Cavintonum ® contains lactose. In case of intolerance to lactose should note that one tablet contains 41.50 mg of lactose monohydrate.
The action of the drug on the ability to drive: data on the effect of Vinpocetine on the ability to drive a car and anavar cycle for women working mechanisms, not.
Tablets of 5 mg.
Of 25 tablets in a blister made ??of PVC / Al. 2 blisters in a cardboard box with instructions for use
Do not use beyond the expiration date printed on the package.
At a temperature of 15-30 ° C, in a dark place, out of reach of children.
Conditions of supply of pharmacies